Grants

Title of Project: Evaluating DUX4 as a Therapeutic Target for FSHD

Principal Investigator: Dr. Charles Emerson

Granting Agency: Muscular Dystrophy Association

Grant Period: 2/1/12 – 1/31/15

(A press release from the Muscular Dystrophy Association can be found at  http://mda.org/research/gaag/2012/fshd-emerson.html.)

 

Title of Project: CMD & LGMD Therapeutic Targets: Model Studies

Principal Investigator: Dr. Jeffrey B. Miller

Granting Agency: Muscular Dystrophy Association

Grant Period: 2/1/12 – 1/31/15

(A press release from the Muscular Dystrophy Association can be found at http://mda.org/research/gaag/2012/cmd-lgmd-miller.html.)

 

Title of Project: Regulation of Myosin-X

Principal Investigator: Dr. Hiroshi Tokuo

Granting Agency: NIH

Grant Period: 8/25/11 - 7/31/14

 

Title of Project: Analysis of DUX4-fl Expression

Principal Investigator: Dr. Peter L. Jones

Granting Agency: FSH Society, Inc.

Grant Period: 8/11 - 8/12

 

Title of Project: Control of Muscle Protein Synthesis During Myogenesis

Principal Investigator: Dr. Charles P. Emerson, Jr.

Granting Agency: NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development

Grant Period: 9/20/10 - 5/31/15

 

Title of Project: Molecular Mechanism of FSHD Pathology

Principal Investigator: Dr. Peter L. Jones

Granting Agency: NIH/ National Institute of Arthritis and Musculoskeletal and Skin Diseases

Grant Period: 9/1/10 - 8/31/12

 

Title of Project: The Role of Proteases and Peptides in Cancer Pain

Principal Investigator: Dr. Markus Hardt

Granting Agency: NIH/ Institute of Dental and Craniofacial Research

Grant Period: 9/1/10 - 8/31/15

 

Title of Project: Molecular basis of ADCC- mediated HIV Protection

Principal Investigator: Dr. Eric Sundberg

Granting Agency: NIH/ National Institute of Allergy and Infectious Diseases

Grant Period: 7/2/10 - 6/30/14

 

Title of Project: Molecular basis of myelomonocytic receptor function in HIV-1 infection

Principal Investigator: Dr. Eric Sundberg

Granting Agency: NIH

Grant Period: 12/1/09 - 11/30/14

 

Title of Project: Biomarkers for Therapy of FSHD (U54) (ARRA Award)

Principal Investigator: Dr. Charles P. Emerson
Granting Agency: NIH/ARRA/Eunice Kennedy Shriver National Institute of Child Health and Human Development
Grant Period: 9/30/09-9/29/11

 

Title of Project: Differential regulation of cardiomyocyte survival and hypertrophy (ARRA Award)
Principal Investigator: Dr. Peter Erhardt
Granting Agency: NIH/ARRA/National Heart, Lung and Blood Institute
Grant Period: 9/1/09 - 8/31/11

 

Title of Project: NIH Director Pioneer Award (ARRA Award)
Principal Investigator: Dr. James L. Sherley
Granting Agency: NIH/ARRA/Office of the Director, National Institutes of Health
Grant Period: 7/20/09 - 9/30/10

 

Title of Project: The Role of PtdIns-5P in Cell Function and Signaling (ARRA Award)
Principal Investigator: Dr. Lucia Rameh-Plant
Granting Agency: NIH/ARRA/National Institute of Diabetes and Digestive and Kidney Disorders
Grant Period: 7/17/09 - 6/30/11

 

Title of Project: Role of Myosin 1c in Adaptation in the Inner Ear (ARRA Award)
Principal Investigator: Dr. Lynne M. Coluccio
Granting Agency: NIH/ARRA/National Institute on Deafness and Other Communication Disorders
Grant Period: 7/17/09 - 6/30/11

 

Title of Project: Intein Inhibitors as Potential TB Drugs
Principal Investigator: Dr. Henry Paulus
Granting Agency: NIH/National Institute of Mental Health
Grant Period: 7/15/09 - 6/30/10

 

Title of Project: Integrative Behavioral, Computational, and Molecular Approach for Identifying Signatures of Neurodegenerative Disorders
Principal Investigator: Dr. Martin Duennwald, Dr. Oliver King, Dr. Moonkyoung Um
Granting Agency: Anonymous Foundation
Grant Period: 7/1/09 - 6/30/10

 

Title of Project: The Systems Biology of Age-dependent Protein Misfolding
Principal Investigator: Dr. Martin Duennwald
Granting Agency: American Federation for Aging Research (AFAR)
Grant Period: 7/1/09 - 6/30/11

 

Title of Project: Identification of Inhibitors of Hedgehog Autoprocessing
Principal Investigator: Dr. Henry Paulus, Dr. Charles P. Emerson
Granting Agency: NIH/National Institute of Neurological Disorders and Stroke
Grant Period: 7/1/09 - 6/30/11

 

Title of Project: Control of Muscle Protein Synthesis during Myogenesis (ARRA Award)
Principal Investigator: Dr. Charles P. Emerson
Granting Agency: NIH/ARRA/Eunice Kennedy Shriver National Institute of Child Health and Human Development
Grant Period: 6/1/09 - 10/31/09

 

Title of Project: Tropomyosin and the Regulation of Muscle Contraction (ARRA Award)
Principal Investigator: Dr. Sherwin Lehrer
Granting Agency: NIH/ARRA/National Heart, Lung and Blood Institute
Grant Period: 6/1/09 - 10/31/09

 

Title of Project: MDC1A Therapeutic Mechanisms: Model Studies
Principal Investigator: Dr. Jeffrey Miller
Granting Agency: Muscular Dystrophy Association
Grant Period: 01/01/09-12/31/11

 

Title of Project: Troponin & Myosin in Regulation of Muscle Contraction and Heart Disease
Principal Investigator: Dr. Zenon Grabarek
Granting Agency: NIH/National Heart, Lung, and Blood Institute
Grant Period: 12/15/08 - 11/30/12

 

Title of Project: Regulation of Vascular Smooth Muscle Cytoskeleton
Principal Investigator: Dr. Albert Wang
Granting Agency: NIH/National Heart/Lung, and Blood Institute
Grant Period: 12/1/08 - 11/30/12

 

Title of Project: Insulin-like Growth Factor 1 Vaccine for Cancer Prevention
Principal Investigator: Dr. Victor Raso
Granting Agency: NIH/National Cancer Institute
Grant Period: 09/22/08-08/31/10

 

Title of Project: Development of Superantigen Antagonists
Principal Investigator: Dr. Eric Sundberg
Granting Agency: NIH/National Institute of Allergy and Infectious Diseases
Grant Period: 09/15/08-08/31/12

 

Title of Project: The Role of PtdIns-5-P in Cell Function and Signaling
Principal Investigator: Dr. Lucia Rameh-Plant
Granting Agency: NIH/National Institute of Diabetes and Digestive and Kidney Diseases
Grant Period: 09/15/08-08/31/13

 

Title of Project: Biomarkers for Therapy of FSHD (U54)
Principal Investigator: Dr. Charles P. Emerson
Granting Agency: NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development
Grant Period: 09/10/08-08/31/13

 

Title of Project: A FRET-Based Assay to Measure Dynamic Changes in RyR1 Structure
Principal Investigator: Dr. James Fessenden
Granting Agency: NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases
Grant Period: 08/01/08-04/30/10

 

Title of Project: Role of Myosin 1c in Adaptation in the Inner Ear
Principal Investigator: Dr. Lynne Coluccio
Granting Agency: NIH/National Institute on Deafness and Other Communication Disorders
Grant Period: 07/01/08-06/30/13